Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.68 |
| ▸ | NPC1 | O15118 | 9/20 | 0.63 |
| ▸ | SCD | O00767 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | METAP2 | P50579 | 1/20 | 0.57 |
| ▸ | METAP1 | P53582 | 1/20 | 0.57 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | AGER | Q15109 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995829 | 0.78 | NPC1 (1.00) | RAB9ANPC1SCDSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL27594584 | 0.76 | NPC1 (0.97) | RAB9ANPC1SCDSMN1; SMN2LMNA | |
| SCHEMBL16562033 | 0.76 | SCD (1.00) | RAB9ANPC1SCDSMN1; SMN2LMNA | |
| SCHEMBL2628996 | 0.74 | NPC1 (0.76) | RAB9ANPC1SCDSMN1; SMN2LMNA | |
| SCHEMBL29904457 | 0.73 | HSPA5 (0.71) | RAB9ANPC1SCDSMN1; SMN2LMNA | |
| SCHEMBL8558332 | 0.73 | HSPA5 (0.71) | RAB9ANPC1SCDSMN1; SMN2LMNA | |
| SCHEMBL4290771 | 0.73 | NPC1 (0.79) | RAB9ANPC1SCDSMN1; SMN2LMNA | |
| SCHEMBL1897970 | 0.73 | NPC1 (1.00) | RAB9ANPC1SCDSMN1; SMN2LMNA | |
| SCHEMBL2658062 | 0.73 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5753873 | 0.73 | KCNMA1 (0.46) | RAB9ANPC1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155720-A1 | PYRROLE-2-CARBOXAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | Advinus Therapeutics Private Limited (IN) | 2010-02-24 | — | — | EP | claimed |
| WO-2008149382-A1 | PYRROLE-2-CARBOXAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2008-12-11 | — | — | WO | claimed |