Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615785 | 0.93 | AKR1C3 (0.73) | AKR1C3AKR1C2TUBB1LMNACYP1A2 | |
| SCHEMBL11613879 | 0.91 | TUBB1 (0.75) | AKR1C3AKR1C2TUBB1LMNACYP1A2 | |
| SCHEMBL16746715 | 0.78 | AKR1C3 (0.81) | AKR1C3AKR1C2TUBB1PTGS1ALDH1A1 | |
| Acetic Acid SCHEMBL11761270 | 0.78 | AKR1C3 (0.93) | AKR1C3AKR1C2TUBB1LMNACYP1A2 | |
| SCHEMBL11612929 | 0.77 | LMNA (0.68) | AKR1C3AKR1C2LMNACYP1A2CYP2D6 | |
| SCHEMBL11827602 | 0.77 | AKR1C3 (0.67) | AKR1C3AKR1C2TUBB1LMNACYP1A2 | |
| SCHEMBL29941900 | 0.76 | AKR1C3 (0.77) | AKR1C3AKR1C2TUBB1LMNACYP1A2 | |
| SCHEMBL11037919 | 0.76 | AKR1C3 (1.00) | AKR1C3AKR1C2TUBB1LMNACYP1A2 | |
| SCHEMBL29481380 | 0.76 | AKR1C3 (1.00) | AKR1C3AKR1C2TUBB1LMNACYP1A2 | |
| SCHEMBL3915235 | 0.75 | TUBB1 (1.00) | AKR1C3AKR1C2TUBB1ELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104278-A | Process for the production of compounds with antiphlogistic activity | TROPONWERKE DINKLAGE & CO. (DE) | 1978-08-01 | — | — | US | disclosed |