Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.62 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615788 | 0.94 | PTGS2 (0.73) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL11613881 | 0.92 | LMNA (0.58) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL1082631 | 0.82 | HIF1A (1.00) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL29373123 | 0.82 | PTGS2 (0.80) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| Hydrochloric Acid SCHEMBL8646699 | 0.81 | HIF1A (0.98) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL10909072 | 0.81 | PTGS2 (0.83) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL23391007 | 0.80 | LMNA (0.83) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL31262996 | 0.79 | PTGS2 (0.72) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL12949361 | 0.79 | LMNA (0.80) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL6102416 | 0.79 | AKR1C3 (0.84) | LMNACYP1A2CYP2D6CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104278-A | Process for the production of compounds with antiphlogistic activity | TROPONWERKE DINKLAGE & CO. (DE) | 1978-08-01 | — | — | US | disclosed |