Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.75 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.39 |
| ▸ | TUBB | P07437 | 3/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612927 | 0.91 | AKR1C3 (0.60) | TUBB1AKR1C3AKR1C2ALDH1A1CYP1A2 | |
| SCHEMBL3915235 | 0.87 | TUBB1 (1.00) | TUBB1AKR1C3AKR1C2ALDH1A1L3MBTL1 | |
| SCHEMBL11615785 | 0.86 | AKR1C3 (0.73) | TUBB1AKR1C3AKR1C2CYP1A2LMNA | |
| SCHEMBL11613881 | 0.79 | LMNA (0.58) | AKR1C3AKR1C2CYP1A2LMNACYP2D6 | |
| SCHEMBL3914982 | 0.78 | TUBB1 (0.81) | TUBB1AKR1C3AKR1C2ALDH1A1L3MBTL1 | |
| SCHEMBL16746715 | 0.72 | AKR1C3 (0.81) | TUBB1AKR1C3AKR1C2ALDH1A1L3MBTL1 | |
| SCHEMBL11827602 | 0.72 | AKR1C3 (0.67) | TUBB1AKR1C3AKR1C2CYP1A2LMNA | |
| SCHEMBL11613875 | 0.72 | LMNA (0.46) | TUBB1AKR1C3AKR1C2CYP1A2LMNA | |
| Acetic Acid SCHEMBL11761270 | 0.71 | AKR1C3 (0.93) | TUBB1AKR1C3AKR1C2CYP1A2LMNA | |
| SCHEMBL11612929 | 0.70 | LMNA (0.68) | AKR1C3AKR1C2CYP1A2LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104278-A | Process for the production of compounds with antiphlogistic activity | TROPONWERKE DINKLAGE & CO. (DE) | 1978-08-01 | — | — | US | disclosed |