Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23950938 | 0.81 | ABCG2 (0.55) | RAB9AHSP90AA1HSP90AB1ADORA2AADORA1 | |
| SCHEMBL4801904 | 0.80 | RAB9A (0.73) | RAB9AHSP90AA1HSP90AB1ADORA2AADORA1 | |
| SCHEMBL9492310 | 0.79 | LMNA (0.47) | RAB9APOLBIDO1ABCG2ABCC1 | |
| SCHEMBL11613266 | 0.78 | RAB9A (0.51) | RAB9AHSP90AA1HSP90AB1ADORA2AADORA1 | |
| SCHEMBL2305317 | 0.76 | IDO1 (0.43) | RAB9AADORA2AADORA1POLBIDO1 | |
| SCHEMBL671052 | 0.76 | RAB9A (1.00) | RAB9AADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL24721381 | 0.75 | MAP4K4 (0.59) | ADORA2AADORA1IDO1ABCG2ABCC1 | |
| SCHEMBL3421554 | 0.75 | RAB9A (0.66) | RAB9AADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL1130756 | 0.75 | IDO1 (0.42) | RAB9AADORA2AADORA1IDO1NPC1 | |
| SCHEMBL25775016 | 0.73 | L3MBTL1 (0.55) | RAB9AHSP90AA1HSP90AB1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103009-A | ANTIULCER AGENTS, DIURETICS | NIPPON SHINYAKU CO., LTD. (JP) | 1978-07-25 | — | — | US | claimed |
| US-4103009-A | ANTIULCER AGENTS, DIURETICS | NIPPON SHINYAKU CO., LTD. (JP) | 1978-07-25 | — | — | US | disclosed |