Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | CCR2 | P41597 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11613651 | 1.00 | KDM4E (0.46) | KDM4EPOLBPKMGPR35ABCB11 | |
| SCHEMBL11613402 | 0.85 | ALDH1A1 (0.42) | KDM4EPOLBPKMHSD17B10 | |
| SCHEMBL11613405 | 0.85 | ALDH1A1 (0.42) | KDM4EPOLBPKMHSD17B10 | |
| SCHEMBL11617679 | 0.82 | PKM (0.49) | KDM4EPOLBPKMCCR2 | |
| SCHEMBL11617675 | 0.82 | PKM (0.49) | KDM4EPOLBPKMCCR2 | |
| SCHEMBL11615779 | 0.81 | KDM4E (0.45) | KDM4EPOLBPKMGPR35ABCB11 | |
| SCHEMBL11618317 | 0.81 | POLB (0.49) | KDM4EPOLBPKMABCB11SRC | |
| SCHEMBL11613152 | 0.79 | FABP4 (0.47) | KDM4EPOLBPKMABCB11HSD17B10 | |
| SCHEMBL11616435 | 0.77 | PKM (0.42) | KDM4EPOLBPKMGPR35ABCB11 | |
| SCHEMBL11621960 | 0.76 | POLB (0.42) | KDM4EPOLBPKMGPR35ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | disclosed |