Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612923 | 0.91 | LMNA (0.55) | LMNACYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL11615782 | 0.87 | PTGS2 (0.59) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL10909068 | 0.79 | LMNA (0.59) | LMNACYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL11613881 | 0.77 | LMNA (0.58) | LMNACYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL5809155 | 0.73 | PTGS2 (0.61) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL11615249 | 0.73 | AKR1C2 (0.48) | AKR1C2MEN1KMT2A | |
| Water SCHEMBL10910165 | 0.72 | PTGS2 (0.60) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL11828310 | 0.72 | PTGS2 (0.60) | LMNACYP1A2CYP2D6CYP2C9HIF1A | |
| SCHEMBL11613879 | 0.72 | TUBB1 (0.75) | LMNACYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL8578367 | 0.71 | LMNA (0.61) | LMNACYP1A2CYP2D6CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104278-A | Process for the production of compounds with antiphlogistic activity | TROPONWERKE DINKLAGE & CO. (DE) | 1978-08-01 | — | — | US | disclosed |