Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784015 | 0.80 | NOTUM (0.37) | TSHR | |
| SCHEMBL7467777 | 0.75 | CYP2A6 (0.46) | CYP1A2CYP2A6 | |
| SCHEMBL17514637 | 0.72 | — | — | |
| SCHEMBL4608811 | 0.72 | METAP2 (0.33) | — | |
| SCHEMBL4284890 | 0.72 | HSD17B1 (0.44) | CYP1A2LMNATSHR | |
| SCHEMBL15635852 | 0.71 | GRIA1 (0.41) | SRCCYP1A2CYP2A6LMNATSHR | |
| SCHEMBL3410410 | 0.71 | TP53 (0.41) | TSHR | |
| SCHEMBL11615995 | 0.71 | FGFR1 (0.33) | FGFR1SRCCYP1A2CYP2A6AHR | |
| SCHEMBL2224527 | 0.71 | ALDH1A1 (0.38) | LMNATSHR | |
| SCHEMBL1977908 | 0.71 | PLA2G7 (0.40) | CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4113879-A | TRIPHENYLMETHANEDICARBOXYLIC ACIDS, ANTI-INFLAMMATORY AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-12 | — | — | US | disclosed |