Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784010 | 0.80 | NOTUM (0.37) | TSHRCHEK1WEE1 | |
| SCHEMBL15635850 | 0.72 | CYP2A6 (0.33) | FGFR1SRCCYP1A2CYP2A6LMNA | |
| SCHEMBL3410408 | 0.72 | TP53 (0.42) | AHRTSHR | |
| SCHEMBL4456396 | 0.71 | ALDH1A1 (0.50) | FGFR1SRCGABRPGABRDGABRA1 | |
| SCHEMBL4445036 | 0.71 | CNR2 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11615997 | 0.71 | FGFR1 (0.33) | FGFR1SRCCYP1A2CYP2A6LMNA | |
| SCHEMBL1274816 | 0.71 | AHR (0.50) | LMNAAHRTSHRHSP90AA1 | |
| SCHEMBL4284888 | 0.69 | HSD17B1 (0.45) | CNR1CYP1A2LMNATSHR | |
| SCHEMBL4608809 | 0.69 | METAP2 (0.34) | — | |
| SCHEMBL17514634 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4113879-A | TRIPHENYLMETHANEDICARBOXYLIC ACIDS, ANTI-INFLAMMATORY AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-12 | — | — | US | disclosed |