Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KIT | P10721 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14484609 | 0.80 | CLK4 (0.51) | MAPTLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL7608689 | 0.80 | ERN1 (0.47) | KMT2AERN1L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL27702973 | 0.80 | FDPS (0.45) | KMT2AMAPTL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL7570350 | 0.79 | DYRK1A (0.55) | MAPTERN1LMNAALDH1A1NPC1 | |
| SCHEMBL28337457 | 0.79 | ABL1 (0.47) | KMT2ATP53MAPTERN1TSHR | |
| SCHEMBL2085980 | 0.78 | NFE2L2 (0.46) | TP53ERN1ALDH1A1NPC1RAB9A | |
| SCHEMBL5917924 | 0.77 | MEN1 (0.55) | KMT2AMAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11619712 | 0.77 | ERN1 (0.51) | KMT2ATP53MAPTERN1L3MBTL1 | |
| SCHEMBL11617702 | 0.77 | KMT2A (0.48) | KMT2ATP53MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL11619840 | 0.76 | FYN (0.49) | KMT2AMAPTL3MBTL1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104275-A | COMPLEXING AGENTS, DISPERSING AGENTS, ANTIVIRAL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-08-01 | — | — | US | disclosed |
| US-4024158-A | 4'-BENZOYLBENZO-18-CROWN-6 | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-05-17 | — | — | US | disclosed |