SCHEMBL14484609

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28337457	0.86	ABL1 (0.47)	CLK4NFE2L2ABL1ABCB1BCR
	SCHEMBL7570350	0.83	DYRK1A (0.55)	CLK4ALDH1A1KDM4EHPGDNFE2L2
	SCHEMBL2083783	0.81	COMT (0.44)	ALDH1A1KDM4ESYKCYP2A6RAB9A
	SCHEMBL11617705	0.80	KMT2A (0.46)	ALDH1A1KDM4EHPGDRAB9ANPC1
	SCHEMBL2083077	0.79	ALDH1A1 (0.42)	ALDH1A1HPGDABL1CYP2A6MAPT
	SCHEMBL14829253	0.78	CLK4 (0.49)	CLK4ALDH1A1KDM4EHPGDSYK
	SCHEMBL24742077	0.78	NFE2L2 (0.42)	NFE2L2RAB9ANPC1MAPT
	SCHEMBL10119498	0.78	TDP1 (0.47)	ALDH1A1KDM4ENFE2L2RAB9ANPC1
	SCHEMBL28753109	0.78	ABL1 (0.40)	KDM4EABL1ABCB1BCRPTPN1
	SCHEMBL30069637	0.78	NFE2L2 (0.42)	NFE2L2RAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.