SCHEMBL11623485

SCHEMBL11623485

COc1nn(-c2ccccc2I)c(=O)o1

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FAAH O00519 12/20 0.55
MGLL Q99685 8/20 0.55
ABHD16A O95870 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30201257 0.83 ABHD16A (0.57) FAAHMGLLABHD16A
SCHEMBL74675 0.83 ABHD16A (0.57) FAAHMGLLABHD16A
SCHEMBL11618467 0.82 FAAH (0.55) FAAHMGLLABHD16A
SCHEMBL11620519 0.82 FAAH (0.55) FAAHMGLLABHD16A
SCHEMBL2237059 0.82 ABHD16A (0.60) FAAHMGLLABHD16A
SCHEMBL11558856 0.79 FAAH (0.52) FAAHMGLLABHD16A
SCHEMBL11620781 0.78 FAAH (0.78) FAAHMGLLABHD16A
SCHEMBL11558642 0.77 ABHD16A (0.51) FAAHMGLLABHD16A
SCHEMBL11619457 0.77 FAAH (0.50) FAAHMGLLABHD16A
SCHEMBL11620913 0.77 MGLL (0.50) FAAHMGLLABHD16A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4076824-A Anthelmintic oxadiazolinone derivatives RHONE-POULENC INDUSTRIES (FR) 1978-02-28 US disclosed