Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616224 | 0.80 | MAOB (0.56) | MAOBMAOAALOX15ALOX12SMN1; SMN2 | |
| SCHEMBL11622080 | 0.76 | MAOB (0.56) | MAOBMAOAALOX15ALOX12 | |
| SCHEMBL11618420 | 0.76 | ALDH1A1 (0.53) | MAOBLMNACYP3A4HPGDALDH1A1 | |
| SCHEMBL11869804 | 0.72 | POLB (0.59) | MAOBLMNACYP1A2CYP3A4HPGD | |
| SCHEMBL21591539 | 0.72 | SMN1; SMN2 (0.59) | MAOBHPGDTSHRALDH1A1ALOX15 | |
| SCHEMBL29473861 | 0.72 | LMNA (0.40) | GABRA1GABRG2GABRB3FAAHCA1 | |
| SCHEMBL31034958 | 0.71 | CES1 (0.38) | MAOBBLMHIF1AMAOAALOX15 | |
| SCHEMBL25003690 | 0.70 | GABRA1 (0.38) | GABRA1GABRG2GABRB3FAAHCA1 | |
| SCHEMBL18235035 | 0.70 | MAOB (0.44) | MAOBHPGDBLMHIF1AALDH1A1 | |
| SCHEMBL18222932 | 0.70 | MAOB (0.44) | MAOBHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098799-A | ANTIALLERGENS, HYPERACIDITY | WARNER-LAMBERT COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4008252-A | ANTIALLERGENS, ANTIHYPERACIDITY | WARNER-LAMBERT COMPANY (US) | 1977-02-15 | — | — | US | disclosed |