Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BRD1 | O95696 | 2/20 | 0.47 |
| ▸ | TAF1 | P21675 | 2/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11619089 | 0.90 | LMNA (0.54) | LMNARECQLBRD1TAF1BRPF1 | |
| SCHEMBL11726873 | 0.89 | LMNA (0.61) | LMNARECQLBRD1TAF1BRPF1 | |
| SCHEMBL18806465 | 0.84 | RECQL (0.62) | LMNARECQLBRD1TAF1BRPF1 | |
| SCHEMBL14893998 | 0.83 | LMNA (0.54) | LMNARECQLSCN2APOLBGRM1 | |
| SCHEMBL11825666 | 0.82 | ALDH1A1 (0.47) | LMNARECQLMEN1KMT2AL3MBTL1 | |
| SCHEMBL3824635 | 0.81 | MEN1 (0.51) | BRD1TAF1BRPF1MEN1KMT2A | |
| SCHEMBL11621303 | 0.80 | CYP3A4 (0.54) | LMNABRD1TAF1BRPF1GRM1 | |
| SCHEMBL11623903 | 0.79 | ALDH1A1 (0.55) | RECQLMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL11726856 | 0.79 | LMNA (0.61) | LMNARECQLBRD1TAF1BRPF1 | |
| SCHEMBL11726838 | 0.76 | CA12 (0.50) | LMNARECQLSCN2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124593-A | ANTICONVULSANTS, EPILEPSY | CIBA-GEIGY CORPORATION (US) | 1978-11-07 | — | — | US | disclosed |
| US-4025505-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-3941883-A | Aromatic dicarboxamides as anticonvulsants | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |