Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | TYMS | P04818 | 2/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BRD1 | O95696 | 1/20 | 0.47 |
| ▸ | TAF1 | P21675 | 1/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726873 | 0.90 | LMNA (0.61) | LMNATDP1POLBMEN1KMT2A | |
| SCHEMBL11619089 | 0.89 | LMNA (0.54) | LMNATDP1POLBMEN1GFER | |
| SCHEMBL14893998 | 0.89 | LMNA (0.54) | LMNATDP1POLBGRM1GRM4 | |
| SCHEMBL10885870 | 0.88 | RECQL (0.59) | LMNATDP1POLBMEN1GFER | |
| SCHEMBL11722682 | 0.82 | MEN1 (0.47) | LMNATDP1POLBMEN1GFER | |
| SCHEMBL12556877 | 0.82 | TDP1 (0.56) | LMNATDP1POLBMEN1GFER | |
| SCHEMBL11825657 | 0.80 | ALDH1A1 (0.47) | LMNATDP1POLBMEN1GFER | |
| SCHEMBL11727066 | 0.79 | DPP4 (0.55) | LMNAMEN1KMT2AGRM1GRM4 | |
| SCHEMBL11723801 | 0.79 | L3MBTL1 (0.70) | TDP1POLBMEN1GFERKMT2A | |
| SCHEMBL11619096 | 0.79 | LMNA (0.54) | LMNATDP1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025505-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-3941883-A | Aromatic dicarboxamides as anticonvulsants | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |