Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11618317 | 0.87 | POLB (0.49) | KDM4EPOLBPKMAPEX1ABCB11 | |
| SCHEMBL11613152 | 0.85 | FABP4 (0.47) | KDM4EPOLBPKMABCB11L3MBTL1 | |
| SCHEMBL11616435 | 0.83 | PKM (0.42) | KDM4EPOLBPKMGLAGPR35 | |
| SCHEMBL11613651 | 0.81 | KDM4E (0.46) | KDM4EPOLBPKMGPR35ABCB11 | |
| SCHEMBL11613646 | 0.81 | KDM4E (0.46) | KDM4EPOLBPKMGPR35ABCB11 | |
| SCHEMBL11619447 | 0.80 | KDM4E (0.46) | KDM4EPOLBPKMGLAFDPS | |
| SCHEMBL11621960 | 0.79 | POLB (0.42) | KDM4EPOLBPKMGPR35ABCB11 | |
| SCHEMBL11617064 | 0.79 | GPR35 (0.49) | KDM4EPOLBPKMGLAGPR35 | |
| SCHEMBL11614682 | 0.74 | TSHR (0.54) | KDM4EPOLBL3MBTL1 | |
| SCHEMBL11621562 | 0.71 | ALDH1A1 (0.48) | KDM4EPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | claimed |