Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | FABP4 | P15090 | 4/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | WEE1 | P30291 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11613152 | 0.92 | FABP4 (0.47) | POLBFABP4FABP5FABP3KDM4E | |
| SCHEMBL11615779 | 0.87 | KDM4E (0.45) | POLBKDM4EL3MBTL1PKMAPEX1 | |
| SCHEMBL11617342 | 0.81 | POLB (0.44) | POLBFABP4FABP5FABP3KDM4E | |
| SCHEMBL11621960 | 0.81 | POLB (0.42) | POLBKDM4EL3MBTL1HSD17B10PKM | |
| SCHEMBL11613646 | 0.81 | KDM4E (0.46) | POLBKDM4EL3MBTL1HSD17B10PKM | |
| SCHEMBL11613651 | 0.81 | KDM4E (0.46) | POLBKDM4EL3MBTL1HSD17B10PKM | |
| SCHEMBL11616435 | 0.80 | PKM (0.42) | POLBKDM4EPKMMAPTABCB11 | |
| SCHEMBL11617064 | 0.79 | GPR35 (0.49) | POLBKDM4EHSD17B10PKMMAPT | |
| SCHEMBL11615933 | 0.74 | RAB9A (0.43) | KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL11617264 | 0.69 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | disclosed |