Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355098 | 0.85 | PTPN1 (0.53) | POLBNPC1GPR35ALOX15ALOX12 | |
| SCHEMBL11621890 | 0.82 | GPR35 (0.41) | POLBNPC1KDM4EALDH1A1GPR35 | |
| SCHEMBL11549214 | 0.80 | PSMB5 (0.44) | POLBNPC1KDM4EALOX15ALOX12 | |
| SCHEMBL11702849 | 0.79 | PTGS1 (0.49) | POLBNPC1KDM4EALOX15TP53 | |
| SCHEMBL11364286 | 0.79 | GPR35 (0.46) | POLBNPC1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10547068 | 0.78 | HNF4A (0.50) | POLBNPC1KDM4EALDH1A1GPR35 | |
| SCHEMBL11556534 | 0.77 | MAOB (0.51) | POLBNPC1KDM4EALDH1A1ALOX15 | |
| SCHEMBL20876257 | 0.74 | IP6K1 (0.41) | POLBNPC1ALOX15ALOX12CASP6 | |
| SCHEMBL11623143 | 0.73 | ALDH1A1 (0.41) | POLBKDM4EALDH1A1HSD17B10ALOX15 | |
| SCHEMBL27458636 | 0.73 | TTR (0.59) | KDM4EALDH1A1HSD17B10HDAC7TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124603-A | ANTIMICROBIAL | RIKER LABORATORIES, INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4067993-A | Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids | RIKER LABORATORIES, INC. (US) | 1978-01-10 | — | — | US | disclosed |