Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATIC | P31939 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355098 | 0.81 | PTPN1 (0.53) | GPR35ALOX12ALOX15NPC1POLB | |
| SCHEMBL10547068 | 0.81 | HNF4A (0.50) | GPR35MAPTKDM4EALOX12ALOX15 | |
| SCHEMBL11619992 | 0.79 | POLB (0.43) | GPR35MAPTKDM4EALOX12ALOX15 | |
| SCHEMBL11621890 | 0.79 | GPR35 (0.41) | GPR35KDM4ESMN1; SMN2ALOX12ALOX15 | |
| SCHEMBL11375380 | 0.76 | PIN1 (0.40) | MAPTKDM4ESMN1; SMN2ALOX12ALOX15 | |
| SCHEMBL10259329 | 0.75 | ALOX15 (0.50) | MAPTKDM4ESMN1; SMN2ALOX12ALOX15 | |
| SCHEMBL2462819 | 0.75 | HNF4A (0.55) | GPR35KDM4ESMN1; SMN2LMNAPDE10A | |
| SCHEMBL8876175 | 0.74 | ALOX15 (0.58) | MAPTKDM4ESMN1; SMN2ALOX12ALOX15 | |
| SCHEMBL19999156 | 0.71 | HPGD (0.57) | GPR35MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL20876257 | 0.71 | IP6K1 (0.41) | ALOX12ALOX15NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298532-A | INTERMEDIATES FOR MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1981-11-03 | — | — | US | disclosed |
| US-4260547-A | MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4231965-A | CHEMICAL INTERMEDIATES FOR MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4154848-A | MICROBIOCIDES, BACTERICIDES | RIKER LABORATORIES, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4128659-A | 2-NITRO-3-PHENYL-BENZOFURANS | RIKER LABORATORIES, INC. (US) | 1978-12-05 | — | — | US | disclosed |