Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876175 | 0.89 | ALOX15 (0.58) | HNF4ADHODHNR4A1NR4A2NR4A3 | |
| SCHEMBL11623441 | 0.88 | GPR35 (0.44) | HNF4ADHODHNR4A1NR4A2NR4A3 | |
| SCHEMBL11619785 | 0.85 | ALOX15 (0.51) | DHODHALOX15ALOX12PSMD14ALDH1A1 | |
| SCHEMBL11621112 | 0.84 | PSMD14 (0.56) | NR4A2PSMD14MAPTALDH1A1KDM4E | |
| SCHEMBL11621083 | 0.81 | MCL1 (0.46) | DHODHPSMD14FABP4ALDH1A1KDM4E | |
| SCHEMBL11355098 | 0.81 | PTPN1 (0.53) | HNF4AALOX15ALOX12GPR35NPC1 | |
| SCHEMBL11364286 | 0.81 | GPR35 (0.46) | HNF4ADHODHALOX15ALOX12MAOB | |
| SCHEMBL11619992 | 0.78 | POLB (0.43) | DHODHALOX15ALOX12MAPTTDP1 | |
| SCHEMBL11621890 | 0.78 | GPR35 (0.41) | HNF4ADHODHALOX15ALOX12ALDH1A1 | |
| SCHEMBL11494946 | 0.77 | ALOX15 (0.51) | ALOX15ALOX12MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829067-A | INHIBITORS OF REFLECTIVE CONTRACTION OF BLADDER | TANABE SEIYAKU CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0270342-A2 | A benzo-furan (or -thiophene) derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |
| US-4157387-A | Dentifrice composition containing an abrasive coated with a cationic water soluble polymer | THE PROCTER & GAMBLE COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4124603-A | ANTIMICROBIAL | RIKER LABORATORIES, INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4110083-A | HARD MINERAL PARTICLES COATED WITH A CATIONIC WATER-SOLUBLE POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4067993-A | Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids | RIKER LABORATORIES, INC. (US) | 1978-01-10 | — | — | US | disclosed |