Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668126 | 1.00 | KDM4E (0.38) | KDM4ECYP1A2ALDH1A1RXRARXRB | |
| SCHEMBL555425 | 1.00 | KDM4E (0.38) | KDM4ECYP1A2ALDH1A1RXRARXRB | |
| SCHEMBL4214182 | 0.78 | HPGD (0.38) | KDM4EALDH1A1TDP1SMN1; SMN2GAA | |
| SCHEMBL8188892 | 0.77 | NOTUM (0.36) | CYP1A2NOTUMTDP1SMN1; SMN2PPARG | |
| Water SCHEMBL8734708 | 0.76 | NOTUM (0.35) | CYP1A2NOTUMTDP1SMN1; SMN2PPARG | |
| SCHEMBL5310850 | 0.73 | ATM (0.38) | KDM4ECYP1A2ALDH1A1RXRARXRB | |
| SCHEMBL697581 | 0.72 | CPT2 (0.35) | KDM4ECYP1A2ALDH1A1TDP1GAA | |
| SCHEMBL12817104 | 0.72 | CPT2 (0.35) | KDM4ECYP1A2ALDH1A1TDP1GAA | |
| Water SCHEMBL28155256 | 0.71 | CPT2 (0.34) | KDM4ECYP1A2ALDH1A1TDP1GAA | |
| SCHEMBL31070064 | 0.71 | EDNRB (0.37) | SMN1; SMN2GAAL3MBTL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075630-A1 | METHOD FOR PRODUCING 3-AMINOPIPERIDINE DIASTEREOMER | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-07-05 | — | — | WO | claimed |
| EP-1024137-B1 | RESOLUTION OF AMINES | ESTEVE LABOR DR (ES) | 2003-09-24 | — | — | EP | claimed |
| US-6187930-B1 | REACTING SELECTED AMINE WITH OPTICALLY ACTIVE ACID SELECTED FROM (+)-DITOLUYL-L-TARTARIC ACID AND/OR (-)-DITOLUYL-L-TARTARIC ACID IN SOLVENT TO FORM DIASTEROISOMERIC SALT, SEPARATING, ISOLATING ENANTIOMER | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2001-02-13 | — | — | US | claimed |
| EP-1024137-A1 | RESOLUTION OF AMINES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2000-08-02 | — | — | EP | claimed |
| US-11897843-B2 | Process for the preparation of enantiomerically enriched 3-aminopiperidine | REUTER CHEMISCHE APPARATEBAU KG | 2024-02-13 | — | — | US | disclosed |
| EP-4289819-A2 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | Reuter Chemische Apparatebau e.K. (DE) | 2023-12-13 | — | — | EP | disclosed |
| EP-3653607-B1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | REUTER CHEMISCHE APPBAU E K (DE) | 2023-10-18 | — | — | EP | disclosed |
| US-20230008387-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | REUTER CHEMISCHE APPARATEBAU KG (DE) | 2023-01-12 | — | — | US | disclosed |
| US-11472770-B2 | Process for the preparation of enantiomerically enriched 3-aminopiperidine | REUTER CHEMISCHE APPARATEBAU KG | 2022-10-18 | — | — | US | disclosed |
| EP-3653607-A2 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | Reuter Chemische Apparatenbau e.K. (DE) | 2020-05-20 | — | — | EP | disclosed |
| US-20200087257-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | REUTER CHEMISCHE APPARATEBAU KG (DE) | 2020-03-19 | — | — | US | disclosed |
| US-10464898-B2 | Process for the preparation of enantiomerically enriched 3-aminopiperidine | REUTER CHEMISCHE APPARATEBAU KG (DE) | 2019-11-05 | — | — | US | disclosed |
| US-20050096318-A1 | Pharmaceutically active morpholinol | GLAXOSMITHKLINE SPA (IT) | 2005-05-05 | — | — | US | disclosed |
| US-6855820-B2 | Pharmaceutically active morpholinol | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-15 | — | — | US | disclosed |
| EP-1024137-B1 | RESOLUTION OF AMINES | ESTEVE LABOR DR (ES) | 2003-09-24 | — | — | EP | disclosed |
| US-20030027827-A1 | Pharmaceutically active morpholinol | SMITHKLINE BEECHAM CORPORATION | 2003-02-06 | — | — | US | disclosed |
| US-6187930-B1 | REACTING SELECTED AMINE WITH OPTICALLY ACTIVE ACID SELECTED FROM (+)-DITOLUYL-L-TARTARIC ACID AND/OR (-)-DITOLUYL-L-TARTARIC ACID IN SOLVENT TO FORM DIASTEROISOMERIC SALT, SEPARATING, ISOLATING ENANTIOMER | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2001-02-13 | — | — | US | disclosed |
| US-6187930-B1 | REACTING SELECTED AMINE WITH OPTICALLY ACTIVE ACID SELECTED FROM (+)-DITOLUYL-L-TARTARIC ACID AND/OR (-)-DITOLUYL-L-TARTARIC ACID IN SOLVENT TO FORM DIASTEROISOMERIC SALT, SEPARATING, ISOLATING ENANTIOMER | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2001-02-13 | — | — | US | disclosed |
| EP-1024137-A1 | RESOLUTION OF AMINES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2000-08-02 | — | — | EP | disclosed |
| EP-1024137-A1 | RESOLUTION OF AMINES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2000-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230008387-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | NPEPPS, AASDHPPT, DNPEP | KDM4E 1366/4885CYP1A2 181/4885ALDH1A1 1655/4885 |
| US-11472770-B2 | Process for the preparation of enantiomerically enriched 3-aminopiperidine | NPEPPS, AASDHPPT, DNPEP | KDM4E 1366/4885CYP1A2 181/4885ALDH1A1 1655/4885 |
| US-11897843-B2 | Process for the preparation of enantiomerically enriched 3-aminopiperidine | NPEPPS, AASDHPPT, DNPEP | KDM4E 1379/4885CYP1A2 178/4885ALDH1A1 1707/4885 |
| US-20050096318-A1 | Pharmaceutically active morpholinol | ACHE, COMT, SNCA | KDM4E 490/4885CYP1A2 988/4885ALDH1A1 1559/4885 |
| US-20200087257-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED 3-AMINOPIPERIDINE | NPEPPS, AASDHPPT, DNPEP | KDM4E 1366/4885CYP1A2 181/4885ALDH1A1 1655/4885 |
| US-20030027827-A1 | Pharmaceutically active morpholinol | ACHE, COMT, MGLL | KDM4E 532/4885CYP1A2 919/4885ALDH1A1 1734/4885 |
| US-10464898-B2 | Process for the preparation of enantiomerically enriched 3-aminopiperidine | NPEPPS, AASDHPPT, DNPEP | KDM4E 1395/4885CYP1A2 207/4885ALDH1A1 1791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.