SCHEMBL11623178

SCHEMBL11623178

Cc1ccc(CC2CC(=O)N(SC(Cl)(Cl)Cl)C2=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.49
ALDH1A1 P00352 6/20 0.47
USP2 O75604 1/20 0.47
PKM P14618 1/20 0.47
MAPK1 P28482 1/20 0.47
RECQL P46063 1/20 0.46
POLB P06746 2/20 0.44
TSHR P16473 2/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11626812 0.87 POLB (0.39) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL11628707 0.86 ALDH1A1 (0.50) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL11625009 0.73 MAPT (0.57) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL20814239 0.68 POLB (0.67) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL11625654 0.64 KMT2A (0.53) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL15448808 0.64 ALDH1A1 (0.78) L3MBTL1MEN1KMT2AALDH1A1RECQL
SCHEMBL11626318 0.63 TSHR (0.39) KMT2ASMN1; SMN2ALDH1A1MAPK1TSHR
SCHEMBL19050082 0.61 L3MBTL1 (0.44) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL11473643 0.61 L3MBTL1 (0.44) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL11627271 0.61 GLA (0.64) L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4122185-A 2-Phenyl- and 2-benzyl-N-[(trichloromethyl)thio]succinimides, and fungicidal compositions thereof STERLING DRUG INC. (US) 1978-10-24 US claimed
US-4122185-A 2-Phenyl- and 2-benzyl-N-[(trichloromethyl)thio]succinimides, and fungicidal compositions thereof STERLING DRUG INC. (US) 1978-10-24 US disclosed