Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 4/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623718 | 0.84 | L3MBTL1 (0.39) | TSHRKMT2AALDH1A1LMNATP53 | |
| SCHEMBL11625654 | 0.74 | KMT2A (0.53) | TSHRKMT2AALDH1A1LMNATP53 | |
| SCHEMBL11626812 | 0.67 | POLB (0.39) | TSHRKMT2AALDH1A1LMNATP53 | |
| SCHEMBL16283604 | 0.64 | MAPT (0.41) | TSHRKMT2AALDH1A1LMNATP53 | |
| SCHEMBL11625009 | 0.63 | MAPT (0.57) | TSHRKMT2AALDH1A1LMNATP53 | |
| SCHEMBL11625994 | 0.62 | BRD4 (0.41) | LMNA | |
| SCHEMBL4248469 | 0.62 | NFKB1 (0.38) | KMT2ALMNAMAPK1HIF1AMT-CO2 | |
| SCHEMBL9932801 | 0.62 | ALDH1A1 (0.36) | KMT2AALDH1A1HPGDMAPK1HIF1A | |
| SCHEMBL9669676 | 0.62 | CYP2C19 (0.39) | KMT2AALDH1A1TP53HPGDMAPK1 | |
| SCHEMBL10909815 | 0.61 | ALDH1A1 (0.38) | TSHRKMT2AALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122185-A | 2-Phenyl- and 2-benzyl-N-[(trichloromethyl)thio]succinimides, and fungicidal compositions thereof | STERLING DRUG INC. (US) | 1978-10-24 | — | — | US | claimed |
| US-4122185-A | 2-Phenyl- and 2-benzyl-N-[(trichloromethyl)thio]succinimides, and fungicidal compositions thereof | STERLING DRUG INC. (US) | 1978-10-24 | — | — | US | disclosed |