Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623178 | 0.73 | L3MBTL1 (0.52) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL11255607 | 0.67 | MAPT (0.56) | MAPTALDH1A1POLBHTTKMT2A | |
| SCHEMBL11625654 | 0.64 | KMT2A (0.53) | MAPTALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL11626318 | 0.63 | TSHR (0.39) | ALDH1A1HTTKMT2ASMN1; SMN2TSHR | |
| SCHEMBL13040955 | 0.61 | ALDH1A1 (0.68) | MAPTALDH1A1POLBHTTKMT2A | |
| SCHEMBL11626812 | 0.60 | POLB (0.39) | ALDH1A1POLBHTTKMT2AMEN1 | |
| SCHEMBL9863928 | 0.57 | ALDH1A1 (0.47) | ALDH1A1HTTKMT2ATSHRLMNA | |
| SCHEMBL18415615 | 0.56 | RAB9A (0.56) | MAPTALDH1A1POLBHTTKMT2A | |
| SCHEMBL21965448 | 0.56 | DDB1 (0.72) | GAATSHR | |
| SCHEMBL20194480 | 0.56 | RAB9A (0.56) | MAPTALDH1A1POLBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122185-A | 2-Phenyl- and 2-benzyl-N-[(trichloromethyl)thio]succinimides, and fungicidal compositions thereof | STERLING DRUG INC. (US) | 1978-10-24 | — | — | US | disclosed |