SCHEMBL11623525

SCHEMBL11623525

COc1nn(-c2ccsc2C)c(=O)o1

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ABHD16A O95870 2/20 0.51
FAAH O00519 13/20 0.47
MGLL Q99685 7/20 0.47
LPL P06858 1/20 0.39
LIPC P11150 1/20 0.39
LIPE Q05469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11619465 0.83 ABHD16A (0.49) ABHD16AFAAHMGLLLPLLIPC
SCHEMBL2237059 0.72 ABHD16A (0.60) ABHD16AFAAHMGLL
SCHEMBL11620519 0.72 FAAH (0.55) ABHD16AFAAHMGLL
SCHEMBL11623485 0.72 FAAH (0.55) ABHD16AFAAHMGLL
SCHEMBL7044057 0.71 ABHD16A (0.49) ABHD16AFAAHMGLLLPLLIPC
SCHEMBL11620781 0.70 FAAH (0.78) ABHD16AFAAHMGLLLPLLIPC
SCHEMBL11620913 0.70 MGLL (0.50) ABHD16AFAAHMGLLLPLLIPC
SCHEMBL11619464 0.69 ABHD16A (0.49) ABHD16AFAAHMGLL
SCHEMBL11036133 0.68 KDM4E (0.49) ABHD16AFAAHMGLLLIPCLIPE
SCHEMBL2233598 0.68 ABHD16A (0.72) ABHD16AFAAHMGLLLPLLIPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4076824-A Anthelmintic oxadiazolinone derivatives RHONE-POULENC INDUSTRIES (FR) 1978-02-28 US claimed
US-4076824-A Anthelmintic oxadiazolinone derivatives RHONE-POULENC INDUSTRIES (FR) 1978-02-28 US disclosed