Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | DBH | P09172 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617928 | 0.88 | SMN1; SMN2 (0.45) | PNMTALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL11619242 | 0.86 | P2RX7 (0.39) | P2RX7 | |
| SCHEMBL11581250 | 0.83 | NPSR1 (0.45) | ALDH1A1KDM4EPOLBCYP2A13TAAR1 | |
| SCHEMBL11620133 | 0.79 | DAO (0.46) | ALDH1A1KDM4EP2RX7DBHCYP2A13 | |
| SCHEMBL11619453 | 0.78 | NOX4 (0.43) | POLBP2RX7DBHTSHRCCR2 | |
| SCHEMBL11622380 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EP2RX7SMN1; SMN2 | |
| SCHEMBL11622442 | 0.76 | PTGS1 (0.46) | ALDH1A1KDM4EPOLBP2RX7CYP2A13 | |
| SCHEMBL11617297 | 0.76 | L3MBTL1 (0.45) | ALDH1A1KDM4EPOLBLMNATSHR | |
| SCHEMBL11618566 | 0.75 | MEN1 (0.33) | ALDH1A1ALOX15 | |
| SCHEMBL11623418 | 0.75 | MAPT (0.49) | PNMTKDM4EDBH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076943-A | DIURETICS, SALURETICS, ANTIHYPERTENSIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-02-28 | — | — | US | disclosed |
| US-4061653-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |