Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667374 | 0.88 | OPRK1 (0.41) | OPRK1HPGDTDP1MAOAMAOB | |
| SCHEMBL11630519 | 0.83 | OPRK1 (0.51) | OPRK1MAOAMAOBGLSHSD11B1 | |
| SCHEMBL4247854 | 0.80 | RAB9A (0.50) | HPGDTDP1MAOBRAB9ASMN1; SMN2 | |
| SCHEMBL11628051 | 0.80 | SMN1; SMN2 (0.55) | OPRK1HPGDMAOAMAOBGRIN2D | |
| SCHEMBL3574513 | 0.79 | TDP1 (0.50) | OPRK1HSD17B10TDP1MAOALMNA | |
| SCHEMBL951920 | 0.79 | LMNA (0.56) | HSD17B10MAOAMAOBGRIN2DGRIN3B | |
| SCHEMBL195224 | 0.78 | LMNA (0.58) | LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL10660877 | 0.78 | HSD17B10 (0.44) | HSD17B10HPGDTDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11628529 | 0.77 | LTB4R (0.45) | OPRK1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5711616 | 0.77 | MAOA (0.48) | OPRK1MAOAMAOBGLSHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119776-A1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |
| US-4067726-A | 3-Ureido phenylacetamide herbicides | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |