Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246639 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2SIGMAR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28539349 | 0.79 | CHRM2 (0.50) | SMN1; SMN2SIGMAR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL936317 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2SIGMAR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11764142 | 0.78 | KMT2A (0.53) | SMN1; SMN2SIGMAR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11621137 | 0.76 | KCNN4 (0.46) | SMN1; SMN2SIGMAR1CYP2C19CHRM4CHRM5 | |
| SCHEMBL7809644 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2SIGMAR1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11623260 | 0.74 | ALDH1A1 (0.56) | SMN1; SMN2SIGMAR1CYP2D6CHRM4CHRM5 | |
| SCHEMBL11524611 | 0.73 | TSHR (0.40) | SMN1; SMN2CYP2C9CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL812741 | 0.73 | TSHR (0.40) | CYP2D6CYP2C9CYP2C19KMT2AALDH1A1 | |
| SCHEMBL11764401 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2SIGMAR1CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4094908-A | Alpha-substituted benzhydrol derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1978-06-13 | — | — | US | disclosed |
| US-4039589-A | LIVER MICROSOMAL ENZYMES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1977-08-02 | — | — | US | disclosed |