Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 6/20 | 0.46 |
| ▸ | HTR7 | P34969 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800063 | 0.89 | HTR1A (0.56) | ADRA1DADRA1AADRA1BHTR1AHTR7 | |
| SCHEMBL11630745 | 0.87 | ABCC1 (0.50) | ADRA1DADRA1AADRA1BABCC1HTR1A | |
| SCHEMBL11630022 | 0.87 | ABCC1 (0.49) | ADRA1DADRA1AADRA1BABCC1HTR1A | |
| Hydrochloric Acid SCHEMBL11634209 | 0.86 | ABCC1 (0.49) | ADRA1DADRA1AADRA1BABCC1HTR1A | |
| SCHEMBL11630910 | 0.85 | ADRA1D (0.58) | ADRA1DADRA1AADRA1BHTR1AHTR7 | |
| SCHEMBL11631240 | 0.83 | ABCC1 (0.54) | ABCC1HTR1ADRD2HTR2BHTR2A | |
| SCHEMBL11630455 | 0.83 | TSHR (0.56) | HTR1AHTR7DRD2HTR2A | |
| Hydrochloric Acid SCHEMBL11626439 | 0.82 | ABCC1 (0.53) | ABCC1HTR1ADRD2HTR2BDRD3 | |
| SCHEMBL11627928 | 0.82 | HTR1A (0.52) | ADRA1DADRA1AADRA1BHTR1AHTR7 | |
| SCHEMBL11633843 | 0.81 | ALDH1A1 (0.58) | ABCC1HTR1AHTR7DRD2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092416-A | Benzopyrone derivatives exhibiting anti-allergic activity | BOEHRINGER MANNHEIM GMBH (DT) | 1978-05-30 | — | — | US | disclosed |