Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.52 |
| ▸ | HTR7 | P34969 | 5/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800063 | 0.92 | HTR1A (0.56) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11629707 | 0.86 | HTR1A (0.60) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11630910 | 0.85 | ADRA1D (0.58) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL8799216 | 0.85 | HTR1A (0.48) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11630022 | 0.85 | ABCC1 (0.49) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11630745 | 0.85 | ABCC1 (0.50) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL11634209 | 0.84 | ABCC1 (0.49) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11625995 | 0.84 | HTR1A (0.51) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11632102 | 0.83 | MEN1 (0.64) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11633843 | 0.83 | ALDH1A1 (0.58) | HTR1AHTR7HTR2BHTR6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092416-A | Benzopyrone derivatives exhibiting anti-allergic activity | BOEHRINGER MANNHEIM GMBH (DT) | 1978-05-30 | — | — | US | disclosed |