Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.57 |
| ▸ | HTR7 | P34969 | 3/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800063 | 0.91 | HTR1A (0.56) | HTR1AHTR7HTR6DRD2 | |
| SCHEMBL3398900 | 0.89 | HTR1A (0.65) | ALDH1A1MEN1KMT2AHTR1AHTR7 | |
| SCHEMBL11630910 | 0.85 | ADRA1D (0.58) | ALDH1A1MEN1KMT2AHTR1AHTR7 | |
| SCHEMBL11630745 | 0.84 | ABCC1 (0.50) | HTR1AHTR7HTR6ABCC1DRD2 | |
| SCHEMBL11630022 | 0.84 | ABCC1 (0.49) | HTR1AHTR7ABCC1DRD2DRD4 | |
| SCHEMBL11627928 | 0.83 | HTR1A (0.52) | HTR1AHTR7HTR6HTR2BGAA | |
| Hydrochloric Acid SCHEMBL11634209 | 0.83 | ABCC1 (0.49) | HTR1AHTR7HTR6ABCC1DRD2 | |
| SCHEMBL11629833 | 0.81 | ADRA1D (0.48) | HTR1AHTR7ABCC1DRD2DRD3 | |
| SCHEMBL8799216 | 0.81 | HTR1A (0.48) | ALDH1A1MEN1KMT2AHTR1AHTR7 | |
| SCHEMBL11631240 | 0.81 | ABCC1 (0.54) | ALDH1A1HTR1AMAPTABCC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092416-A | Benzopyrone derivatives exhibiting anti-allergic activity | BOEHRINGER MANNHEIM GMBH (DT) | 1978-05-30 | — | — | US | disclosed |