Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.78 |
| ▸ | GABRD | O14764 | 2/20 | 0.78 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.78 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.78 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.78 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.78 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.78 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.78 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.78 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.78 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.78 |
| ▸ | GABRE | P78334 | 2/20 | 0.78 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.78 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.78 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.78 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936060 | 0.88 | GABRP (0.76) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11061295 | 0.88 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10813064 | 0.88 | GABRP (0.76) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11870764 | 0.86 | GABRP (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15314665 | 0.86 | GABRP (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30661080 | 0.84 | ALDH1A1 (0.71) | CYP1A2CYP2C19MAPTALDH1A1LMNA | |
| SCHEMBL16922182 | 0.84 | ALDH1A1 (0.71) | CYP1A2CYP2C19MAPTALDH1A1LMNA | |
| SCHEMBL5418944 | 0.84 | ALDH1A1 (0.71) | CYP1A2CYP2C19MAPTALDH1A1LMNA | |
| SCHEMBL11824528 | 0.84 | GABRP (0.71) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2987985 | 0.83 | CYP1A2 (0.71) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142506-B1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-10-16 | — | — | EP | claimed |
| US-8394954-B2 | Benzophenone hybrids as anticancer agents and processes for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-12 | — | — | US | claimed |
| US-20100174074-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-07-08 | — | — | US | claimed |
| EP-2142506-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | Council of Scientific&Industrial Research (IN) | 2010-01-13 | — | — | EP | claimed |
| WO-2008120235-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-10-09 | — | — | WO | claimed |
| EP-2061795-B1 | PYRROLO[2,1-C][1,4]BENZODIAZEPINE HYBRIDS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2014-01-15 | — | — | EP | disclosed |
| EP-2142506-B1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-10-16 | — | — | EP | disclosed |
| EP-2142506-B1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-10-16 | — | — | EP | disclosed |
| US-8394954-B2 | Benzophenone hybrids as anticancer agents and processes for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-12 | — | — | US | disclosed |
| US-8394954-B2 | Benzophenone hybrids as anticancer agents and processes for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-12 | — | — | US | disclosed |
| US-8394954-B2 | Benzophenone hybrids as anticancer agents and processes for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-12 | — | — | US | disclosed |
| US-20120128768-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A COMPOUND WITH NPY RECEPTOR AFFINITY AND A COMPOUND WITH 5-HT6 RECEPTOR AFFINITY | LABORATORIOS DEL DR. ESTEVE S.A (ES) | 2012-05-24 | — | — | US | disclosed |
| US-5091415-A | Antiulcer, antisecretory agents | PIERRE FABRE MEDICAMENT (FR) | 1992-02-25 | — | — | US | disclosed |
| US-5075488-A | Fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0128006-B1 | A SOIL-DISEASE-CONTROLLING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-5025015-A | Antisecretory and antiulcer agents | PIERRE FABRE MEDICAMENT (FR) | 1991-06-18 | — | — | US | disclosed |
| US-4709052-A | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-24 | — | — | US | disclosed |
| EP-0143016-B1 | DERIVATIVES OF 4-(3-ALKYNYLOXY-2-HYDROXY-PROPYL)-PIPERAZIN-1-YL-N-PHENYL ACETAMIDE, THEIR PREPARATION AND THEIR THERAPEUTICAL USE | RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) | 1987-07-29 | — | — | EP | disclosed |
| EP-0143016-A1 | Derivatives of 4-(3-alkynyloxy-2-hydroxy-propyl)-piperazin-1-yl-N-phenyl acetamide, their preparation and their therapeutical use | RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) | 1985-05-29 | — | — | EP | disclosed |
| EP-0128006-A2 | A soil-disease-controlling agent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174074-A1 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | TP53, RB1, MCL1 | GABRP 2355/4885GABRD 3476/4885GABRA1 2940/4885 |
| US-20120128768-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A COMPOUND WITH NPY RECEPTOR AFFINITY AND A COMPOUND WITH 5-HT6 RECEPTOR AFFINITY | HTR6, NPY5R, NPY2R | GABRP 191/4885GABRD 340/4885GABRA1 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.