Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.40 |
| ▸ | SELE | P16581 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA7 | P43166 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17301668 | 0.75 | ALOX5 (0.49) | TDP1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL28608448 | 0.73 | CYP3A4 (0.40) | TDP1CA12CA1CA2CA7 | |
| SCHEMBL10768894 | 0.72 | CA12 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5233624 | 0.72 | ALDH1A1 (0.42) | CA12CA1CA2CA7CA9 | |
| Iretol SCHEMBL3190103 | 0.70 | TDP1 (1.00) | TDP1CA12CA1CA2CA7 | |
| SCHEMBL19433124 | 0.70 | CA12 (0.47) | ICAM1SELECA12CA1CA2 | |
| SCHEMBL11312559 | 0.69 | TDP1 (0.60) | TDP1CA12CA1CA2CA7 | |
| SCHEMBL16595967 | 0.69 | MAPT (0.37) | MAPTKMT2A | |
| SCHEMBL11028787 | 0.69 | IRAK4 (0.42) | — | |
| SCHEMBL25329784 | 0.69 | ACHE (0.36) | ICAM1SELECYP3A4MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112003-A | Process for preparing polyphenols | GIVAUDAN CORPORATION (US) | 1978-09-05 | — | — | US | claimed |
| US-4112003-A | Process for preparing polyphenols | GIVAUDAN CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |