SCHEMBL25329784

SCHEMBL25329784

Cc1cc(O)c(C)c(C)c1OC(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
CYP3A4 P08684 2/20 0.35
MAPT P10636 4/20 0.35
LMNA P02545 1/20 0.34
MT-CO2 P00403 1/20 0.34
KDM4E B2RXH2 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
G6PD P11413 1/20 0.33
CYP2C9 P11712 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
CCR6 P51684 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25327700 0.80 SCN5A (0.32) LMNAHPGDALOX15ALOX12MAPK1
SCHEMBL25328780 0.80 SCN5A (0.32) ACHECYP3A4MAPTLMNAMT-CO2
SCHEMBL25329288 0.77 ALOX12 (0.43) ACHECYP3A4MAPTKDM4EALDH1A1
SCHEMBL69787 0.76 CYP3A4 (0.50) ACHECYP3A4MAPTKDM4EHSD17B10
SCHEMBL29093325 0.75 SCN5A (0.56) MAPTSCN5ATP53TRPA1PTGS1
SCHEMBL25328924 0.75 SCN5A (0.47) ACHECYP3A4MAPTLMNAALDH1A1
SCHEMBL25331290 0.73 NPC1 (0.32) LMNAALDH1A1PKMHPGDALOX15
SCHEMBL25329808 0.71 ACHE (0.36) ACHECYP3A4MAPTKDM4EHSD17B10
SCHEMBL25328991 0.71 ALDH1A1 (0.45) ACHECYP3A4MAPTKDM4EHSD17B10
SCHEMBL19372469 0.71 MAPT (0.37) CYP3A4MAPTLMNAKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583813-B2 Polymerization inhibitors BASF SE (DE) 2026-03-24 US disclosed
US-20230242472-A1 POLYMERIZATION INHIBITORS BASF SE (DE) 2023-08-03 US disclosed
EP-4161892-A1 POLYMERIZATION INHIBITORS BASF SE (DE) 2023-04-12 EP disclosed
CN-115697954-A Polymerization inhibitor 巴斯夫欧洲公司 2023-02-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242472-A1 POLYMERIZATION INHIBITORS RCE1, CABLES1, DPYD ACHE 3192/4885CYP3A4 2975/4885MAPT 1359/4885
US-12583813-B2 Polymerization inhibitors PTGS1, PTGER1, POT1 ACHE 4427/4885CYP3A4 1439/4885MAPT 2405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.