Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843230 | 0.85 | NTSR1 (0.52) | LMNACES2CES1HSD17B10MDM2 | |
| SCHEMBL6202553 | 0.84 | LMNA (0.50) | LMNACES2CES1L3MBTL1TDP1 | |
| SCHEMBL28408396 | 0.82 | CYP2C19 (0.53) | LMNACES2CES1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7580361 | 0.80 | L3MBTL1 (0.59) | LMNACES2CES1L3MBTL1TDP1 | |
| SCHEMBL9903761 | 0.79 | L3MBTL1 (0.57) | LMNACES2CES1L3MBTL1TDP1 | |
| SCHEMBL5601491 | 0.77 | ALDH1A1 (0.48) | LMNACES2CES1L3MBTL1TDP1 | |
| SCHEMBL23457200 | 0.77 | L3MBTL1 (0.55) | LMNACES2CES1L3MBTL1TDP1 | |
| SCHEMBL50454 | 0.77 | LMNA (0.80) | LMNACES2CES1L3MBTL1TDP1 | |
| SCHEMBL10833647 | 0.77 | L3MBTL1 (0.55) | LMNACES2CES1L3MBTL1TDP1 | |
| SCHEMBL8859212 | 0.77 | L3MBTL1 (0.55) | LMNACES2CES1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087426-A | Oxybisberberine and a process for its production | RESEARCH CORPORATION (US) | 1978-05-02 | — | — | US | claimed |