Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.42 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11630236 | 0.85 | LMNA (0.55) | NTSR1LMNAHSD17B10KDM4EMDM2 | |
| SCHEMBL30466138 | 0.77 | NTSR1 (0.58) | NTSR1LMNAHSD17B10KDM4EGAA | |
| SCHEMBL6203634 | 0.76 | NTSR1 (0.57) | NTSR1LMNAHSD17B10KDM4EGAA | |
| SCHEMBL11733684 | 0.75 | NTSR1 (0.56) | NTSR1LMNAHSD17B10KDM4EGAA | |
| SCHEMBL11520271 | 0.75 | POLB (0.60) | NTSR1LMNAHSD17B10KDM4EGAA | |
| SCHEMBL11733805 | 0.75 | POLB (0.60) | NTSR1LMNAHSD17B10KDM4EGAA | |
| SCHEMBL11484209 | 0.74 | CES2 (0.59) | LMNAKDM4EMDM2CES2CES1 | |
| SCHEMBL11484197 | 0.74 | CES2 (0.59) | LMNAKDM4EMDM2CES2CES1 | |
| SCHEMBL142538 | 0.73 | CES2 (0.74) | NTSR1LMNAKDM4EGAACES2 | |
| SCHEMBL29989494 | 0.73 | CES2 (0.74) | NTSR1LMNAKDM4EGAACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176393-A1 | Statin-MMP inhibitor combinations | NEWTON ROGER SCHOFIELD (US) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176393-A1 | Statin-MMP inhibitor combinations | MMP9, TIMP3, MMP3 | NTSR1 4111/4885LMNA 1874/4885HSD17B10 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.