Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11630384 | 0.91 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL11632587 | 0.87 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL11631327 | 0.86 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL11629224 | 0.83 | DRD2 (0.56) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL11628957 | 0.81 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL11634699 | 0.81 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL11634977 | 0.80 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL11633834 | 0.80 | CARM1 (0.47) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL11632598 | 0.80 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL11631833 | 0.80 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |