Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11635081 | 0.90 | L3MBTL1 (0.56) | L3MBTL1RAD52ADRA1DADRA1AADRA1B | |
| SCHEMBL11632587 | 0.83 | L3MBTL1 (0.50) | L3MBTL1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL11633309 | 0.82 | RAD52 (0.49) | L3MBTL1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL11629077 | 0.82 | L3MBTL1 (0.56) | L3MBTL1RAD52DRD4ADRA1DADRA1A | |
| SCHEMBL11633867 | 0.80 | L3MBTL1 (0.54) | L3MBTL1HTR7RAD52DRD4KDM4E | |
| SCHEMBL11830608 | 0.80 | KDM4E (0.59) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL11631804 | 0.80 | L3MBTL1 (0.59) | L3MBTL1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL11629079 | 0.80 | L3MBTL1 (0.51) | L3MBTL1HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL11630558 | 0.79 | L3MBTL1 (0.53) | L3MBTL1DRD2RAD52KDM4ELMNA | |
| SCHEMBL11744576 | 0.79 | L3MBTL1 (0.53) | L3MBTL1HTR1ADRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |