Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093837 | 0.89 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3LMNATP53 | |
| SCHEMBL10781283 | 0.83 | ALDH1A1 (0.49) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL8086923 | 0.83 | CALM1 (0.55) | SLC6A2SLC6A4SLC6A3LMNATP53 | |
| SCHEMBL6548117 | 0.82 | HTR2A (0.56) | LMNATP53 | |
| SCHEMBL6547993 | 0.81 | POLB (0.45) | SLC6A2SLC6A4SLC6A3MAPTMEN1 | |
| SCHEMBL11303064 | 0.81 | MAPK1 (0.47) | SLC6A2SLC6A4SLC6A3MAPTMEN1 | |
| SCHEMBL8095786 | 0.81 | LTA4H (0.46) | SLC6A2SLC6A4SLC6A3PTGS2KMT2A | |
| SCHEMBL11205678 | 0.80 | HTR2A (0.54) | LMNATP53 | |
| SCHEMBL11632014 | 0.79 | MEN1 (0.47) | SLC6A2SLC6A4SLC6A3PTGS2MAPT | |
| SCHEMBL608449 | 0.79 | PNMT (0.50) | SLC6A2SLC6A4SLC6A3MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260506-A | Hydraulic pressure device utilizing biodegradable halogenated diphenyl methanes | MONSANTO COMPANY (US) | 1981-04-07 | — | — | US | disclosed |