Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11634736 | 0.94 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11633446 | 0.94 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11629570 | 0.92 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11631767 | 0.91 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11633934 | 0.85 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11633966 | 0.84 | HTR1A (0.56) | L3MBTL1HTR1ASIGMAR1PARP1 | |
| SCHEMBL11629077 | 0.84 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11636616 | 0.83 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11633867 | 0.82 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL11744576 | 0.81 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |