Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631767 | 0.92 | L3MBTL1 (0.47) | L3MBTL1HTR1ALMNAKDM4EMAPT | |
| SCHEMBL11632135 | 0.83 | L3MBTL1 (0.46) | L3MBTL1HTR1ALMNAKDM4EMAPT | |
| SCHEMBL11629570 | 0.83 | L3MBTL1 (0.41) | L3MBTL1HTR1ALMNAKDM4EMAPT | |
| SCHEMBL11634736 | 0.82 | L3MBTL1 (0.44) | L3MBTL1HTR1ALMNAKDM4EMAPT | |
| SCHEMBL11633446 | 0.82 | L3MBTL1 (0.44) | L3MBTL1HTR1AKDM4EMAPTALDH1A1 | |
| SCHEMBL11632587 | 0.82 | L3MBTL1 (0.50) | L3MBTL1HTR1ALMNAKDM4EMAPT | |
| SCHEMBL11632713 | 0.80 | L3MBTL1 (0.47) | L3MBTL1HTR1ALMNAKDM4EHPGD | |
| SCHEMBL11629904 | 0.79 | L3MBTL1 (0.47) | L3MBTL1LMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL11807495 | 0.79 | DRD2 (0.50) | HTR1ALMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL11633966 | 0.79 | HTR1A (0.56) | L3MBTL1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |