Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632135 | 0.92 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL11634736 | 0.86 | L3MBTL1 (0.44) | L3MBTL1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL11633446 | 0.86 | L3MBTL1 (0.44) | L3MBTL1KDM4EALDH1A1MAPTHTR1A | |
| SCHEMBL11630735 | 0.85 | HTR1A (0.48) | L3MBTL1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11631767 | 0.83 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL11636616 | 0.83 | L3MBTL1 (0.42) | L3MBTL1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11633934 | 0.81 | L3MBTL1 (0.39) | L3MBTL1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11634699 | 0.81 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11634610 | 0.80 | L3MBTL1 (0.45) | L3MBTL1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL11805180 | 0.79 | KDM4E (0.56) | L3MBTL1KDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |