Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARD | Q03181 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.55 |
| ▸ | FABP4 | P15090 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfotep SCHEMBL8472533 | 0.98 | GPR84 (0.59) | AKR1B1GPR84PPARGPPARDPPARA | |
| Sulfotep SCHEMBL1163969 | 0.95 | AKR1B1 (0.48) | AKR1B1GPR84PPARGPPARDPPARA | |
| Sulfotep SCHEMBL2026147 | 0.94 | AKR1B1 (0.46) | AKR1B1GPR84PPARGPPARDPPARA | |
| Sulfotep SCHEMBL2336663 | 0.93 | GPR84 (0.48) | AKR1B1GPR84PPARGPPARDPPARA | |
| Sulfotep SCHEMBL2786434 | 0.93 | GPR84 (0.48) | AKR1B1GPR84PPARGPPARDPPARA | |
| Sulfotep SCHEMBL1163295 | 0.87 | FFAR3 (0.52) | AKR1B1GPR84PPARGPPARDPPARA | |
| Sulfotep SCHEMBL7767701 | 0.87 | FFAR3 (0.52) | AKR1B1GPR84PPARGPPARDPPARA | |
| Sulfotep SCHEMBL1163901 | 0.81 | FFAR3 (0.46) | PPARDTSHRALDH1A1TDP1KMT2A | |
| Sulfotep SCHEMBL9651631 | 0.79 | PPARD (0.39) | PPARDTSHRALDH1A1TDP1KMT2A | |
| Sulfotep SCHEMBL5016573 | 0.78 | MEN1 (0.38) | PPARDTSHRALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012057751-A1 | CROSSLINKED CELLULOSIC POLYMERS | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2012-05-03 | — | — | WO | claimed |
| EP-0579089-B1 | Polyether ester amide-sulfur vulcanized rubber compounds | GOODYEAR TIRE & RUBBER (US) | 1996-09-18 | — | — | EP | claimed |
| EP-0579089-A1 | Polyether ester amide-sulfur vulcanized rubber compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-01-19 | — | — | EP | claimed |
| US-5239004-A | A curied addition-condensation copolymer grafted by at least one dithiodiacid; odorless, stiffness, tensile strength | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-08-24 | — | — | US | claimed |
| US-20190209697-A1 | CELLS LABELLED WITH LIPID CONJUGATES AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-07-11 | — | — | US | disclosed |
| EP-3370764-A1 | CELLS LABELLED WITH LIPID CONJUGATES AND METHODS OF USE THEREOF | The Regents of The University of California (US) | 2018-09-12 | — | — | EP | disclosed |
| WO-2017079419-A1 | CELLS LABELLED WITH LIPID CONJUGATES AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-05-11 | — | — | WO | disclosed |
| US-8637468-B2 | Synthetic cholesterylamine-linker derivatives for agent delivery into cells | THE UNIVERSITY OF KANSAS (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130142763-A1 | CROSSLINKED CELLULOSIC POLYMERS | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2013-06-06 | — | — | US | disclosed |
| US-20120208771-A1 | SYNTHETIC CHOLESTERYLAMINE-LINKER DERIVATIVES FOR AGENT DELIVERY INTO CELLS | THE PENN STATE RESEARCH FOUNDATION (US) | 2012-08-16 | — | — | US | disclosed |
| WO-2012057751-A1 | CROSSLINKED CELLULOSIC POLYMERS | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2012-05-03 | — | — | WO | disclosed |
| WO-2011019942-A2 | SYNTHETIC CHOLESTERYLAMINE-LINKER DERIVATIVES FOR AGENT DELIVERY INTO CELLS | UNIVERSITY OF KANSAS (US) | 2011-02-17 | — | — | WO | disclosed |
| EP-0364389-B1 | Nylon modified rubber composition | GOODYEAR TIRE & RUBBER (US) | 1993-12-08 | — | — | EP | disclosed |
| US-5239004-A | A curied addition-condensation copolymer grafted by at least one dithiodiacid; odorless, stiffness, tensile strength | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| US-5238997-A | Increased modulus without detrimental effect on age resistance and hysteresis | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| US-5202384-A | Grafting polyester onto the rubber using a dithiodialkanoic acid; high modulus; stiffness; tensile strength; tire treads; no increased hysteresis | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-04-13 | — | — | US | disclosed |
| US-4996262-A | Improved modulus; reacting epoxidized rubber with polyester | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0390722-A2 | Polyester reinforced rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-10-03 | — | — | EP | disclosed |
| US-4937290-A | Improved modulus | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0364389-A1 | Nylon modified rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209697-A1 | CELLS LABELLED WITH LIPID CONJUGATES AND METHODS OF USE THEREOF | NPC1L1, CETP, LIPA | AKR1B1 1784/4885GPR84 750/4885PPARG 2555/4885 |
| US-20120208771-A1 | SYNTHETIC CHOLESTERYLAMINE-LINKER DERIVATIVES FOR AGENT DELIVERY INTO CELLS | NPC1L1, CETP, CYP46A1 | AKR1B1 1442/4885GPR84 249/4885PPARG 4274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.