Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTR7 | P34969 | 4/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11625995 | 0.91 | HTR1A (0.51) | HTR1ALMNAMAPTHTR7ADRA1D | |
| SCHEMBL8800063 | 0.89 | HTR1A (0.56) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11627928 | 0.85 | HTR1A (0.52) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11630910 | 0.84 | ADRA1D (0.58) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11630022 | 0.82 | ABCC1 (0.49) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11630745 | 0.82 | ABCC1 (0.50) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL11634209 | 0.82 | ABCC1 (0.49) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11629707 | 0.81 | HTR1A (0.60) | HTR1AHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL11633843 | 0.81 | ALDH1A1 (0.58) | HTR1ALMNAMAPTHTR7MAPK1 | |
| SCHEMBL11629833 | 0.79 | ADRA1D (0.48) | HTR1AHTR7ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | claimed |
| US-4092416-A | Benzopyrone derivatives exhibiting anti-allergic activity | BOEHRINGER MANNHEIM GMBH (DT) | 1978-05-30 | — | — | US | claimed |
| CN-108135837-A | For being coated with the Zn composition of microneedle array | 3M创新有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-102917722-B | For being coated with the aqueous formulation of microneedle array | 3M创新有限公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-107012008-A | It is a kind of for foam type engine cleaning agent that can directly discharge of pressurized tank and preparation method thereof | 沈阳市沈北新区朗润汽车养护用品厂 | 2017-08-04 | — | — | CN | disclosed |
| CN-101282941-A | Imidazole compounds for the treatment of neurological disorders | PFIZER (US) | 2008-10-08 | — | — | CN | disclosed |
| CN-1306039-C | Colorimetric method and reagent used therefor | ARKRAY INC (JP) | 2007-03-21 | — | — | CN | disclosed |
| CN-1261588-C | Method of colorimetry and reagent for use therein | ARKRAY INC (JP) | 2006-06-28 | — | — | CN | disclosed |
| CN-1764832-A | Sensor-receiving container | ARKRAY INC (JP) | 2006-04-26 | — | — | CN | disclosed |
| CN-1610753-A | Method of colorimetry and reagent for use therein | ARKRAY INC (JP) | 2005-04-27 | — | — | CN | disclosed |
| CN-1522302-A | Colorimetric method and reagent used therefor | ������������ʽ���� | 2004-08-18 | — | — | CN | disclosed |
| EP-0525123-B1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | UPJOHN CO (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0525123-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES. | UPJOHN CO (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991019707-A2 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1991-12-26 | — | — | WO | disclosed |
| US-4092416-A | Benzopyrone derivatives exhibiting anti-allergic activity | BOEHRINGER MANNHEIM GMBH (DT) | 1978-05-30 | — | — | US | disclosed |