Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 7/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | BRD1 | O95696 | 3/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyanide SCHEMBL25405783 | 0.77 | S100B (0.53) | S100BALDH1A1KDM4ETDP1MAPT | |
| SCHEMBL3136850 | 0.76 | ALDH1A1 (0.90) | ALDH1A1KDM4ETSHRTDP1MAPT | |
| SCHEMBL6603697 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRTDP1FGFR1 | |
| SCHEMBL11639422 | 0.76 | ATAD2 (0.55) | S100BALDH1A1KDM4EMAPTBRPF1 | |
| SCHEMBL28977431 | 0.76 | S100B (0.65) | S100BALDH1A1BRPF1BRD4BRD1 | |
| SCHEMBL26654511 | 0.74 | S100B (0.62) | S100BALDH1A1MAPTHPGDBRPF1 | |
| SCHEMBL10849623 | 0.74 | ALDH1A1 (0.86) | ALDH1A1KDM4ETSHRTDP1MAPT | |
| Asaraldehyde SCHEMBL333451 | 0.72 | ALDH1A1 (1.00) | ALDH1A1KDM4ETSHRTDP1MAPT | |
| Asaraldehyde SCHEMBL29456596 | 0.72 | ALDH1A1 (1.00) | ALDH1A1KDM4ETSHRTDP1MAPT | |
| SCHEMBL22722811 | 0.71 | L3MBTL1 (0.53) | ALDH1A1KDM4ETSHRTDP1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4109008-A | SUBSTITUTED WITH AN AMIDINO AND A 1,3-DIMETHYL-2-OXO-BENZIMIDAZOL- 5-YL RADICAL | HEXACHIMIE (FR) | 1978-08-22 | — | — | US | disclosed |