Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | NGF | P01138 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657546 | 0.80 | ATAD2 (0.71) | ATAD2MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11634100 | 0.76 | S100B (0.59) | MAPTALDH1A1BRD4BRPF1KDM4E | |
| Cyanide SCHEMBL25408115 | 0.74 | ATAD2 (0.49) | ATAD2MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2884919 | 0.72 | GRIA1 (0.56) | MAPTKMT2AMEN1TDP2NGF | |
| SCHEMBL16771511 | 0.71 | ATAD2 (1.00) | ATAD2MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9027928 | 0.71 | ATAD2 (0.64) | ATAD2MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19657544 | 0.71 | ATAD2 (0.59) | ATAD2MAPTALDH1A1SMN1; SMN2BRD4 | |
| SCHEMBL18128766 | 0.70 | GRIA1 (0.54) | MAPTKMT2AMEN1TDP2NGF | |
| SCHEMBL19657848 | 0.69 | ATAD2 (0.57) | ATAD2MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1525859 | 0.68 | ALDH1A1 (0.55) | MAPTALDH1A1SMN1; SMN2BRD4BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4109008-A | SUBSTITUTED WITH AN AMIDINO AND A 1,3-DIMETHYL-2-OXO-BENZIMIDAZOL- 5-YL RADICAL | HEXACHIMIE (FR) | 1978-08-22 | — | — | US | disclosed |