Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PDE6D | O43924 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628957 | 0.91 | L3MBTL1 (0.51) | L3MBTL1KDM4EALDH1A1MAPTMAOB | |
| SCHEMBL11632598 | 0.86 | L3MBTL1 (0.49) | L3MBTL1KDM4EALDH1A1MAPTPDE6D | |
| SCHEMBL11629421 | 0.85 | L3MBTL1 (0.48) | L3MBTL1KDM4EALDH1A1MAPTPDE6D | |
| SCHEMBL11631902 | 0.84 | L3MBTL1 (0.49) | L3MBTL1KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL11634610 | 0.84 | L3MBTL1 (0.45) | L3MBTL1KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL11630384 | 0.81 | L3MBTL1 (0.53) | L3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL11630691 | 0.81 | KDM4E (0.61) | L3MBTL1KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL11629904 | 0.81 | L3MBTL1 (0.47) | L3MBTL1KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL11629570 | 0.81 | L3MBTL1 (0.41) | L3MBTL1KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL11634062 | 0.80 | L3MBTL1 (0.43) | L3MBTL1LMNAALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |