Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11635373 | 1.00 | CYP19A1 (0.48) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL11638086 | 0.86 | ADRA2C (0.51) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL11635085 | 0.86 | ALDH1A1 (0.52) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL11638091 | 0.86 | ADRA2C (0.51) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL11635026 | 0.86 | AGER (0.48) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL11631263 | 0.86 | AGER (0.48) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL11632047 | 0.83 | KMT2A (0.45) | CYP19A1TBXAS1CYP1A2USP2LMNA | |
| SCHEMBL11632050 | 0.83 | KMT2A (0.45) | CYP19A1TBXAS1CYP1A2USP2LMNA | |
| SCHEMBL9532543 | 0.75 | CYP19A1 (0.46) | CYP19A1CYP11B1CYP11B2LMNACYP3A4 | |
| SCHEMBL7562437 | 0.75 | CYP19A1 (0.72) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4078071-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4045568-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-08-30 | — | — | US | disclosed |