SCHEMBL1163584

SCHEMBL1163584

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nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 1/20 0.35
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
TSHR P16473 1/20 0.33
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4274437 1.00 LMNA (0.35) LMNAL3MBTL1ALDH1A1PDE4ATDP1
SCHEMBL4268324 1.00 LMNA (0.35) LMNAL3MBTL1ALDH1A1PDE4ATDP1
SCHEMBL4282241 1.00 LMNA (0.35) LMNAL3MBTL1ALDH1A1PDE4ATDP1
SCHEMBL2722434 1.00 LMNA (0.35) LMNAL3MBTL1ALDH1A1PDE4ATDP1
SCHEMBL111395 1.00 LMNA (0.35) LMNAL3MBTL1ALDH1A1PDE4ATDP1
SCHEMBL27946556 1.00 LMNA (0.35) LMNAL3MBTL1ALDH1A1PDE4ATDP1
SCHEMBL4271266 1.00 LMNA (0.35) LMNAL3MBTL1ALDH1A1PDE4ATDP1
SCHEMBL4274454 0.95 TSHR (0.34) LMNAL3MBTL1ALDH1A1PDE4ATDP1
SCHEMBL4280281 0.95 TSHR (0.34) LMNAL3MBTL1ALDH1A1PDE4ATDP1
SCHEMBL4272338 0.95 TSHR (0.34) LMNAL3MBTL1ALDH1A1PDE4ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11654188-B2 Glycotargeting therapeutics ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2023-05-23 US claimed
US-20090294362-A1 STATIONARY PHASE FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2009-12-03 US claimed
US-20260115300-A1 GLYCOTARGETING THERAPEUTICS ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2026-04-30 US disclosed
US-20260034226-A1 GLYCOTARGETING THERAPEUTICS ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2026-02-05 US disclosed
US-20260007723-A1 GLYCOTARGETING THERAPEUTICS ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2026-01-08 US disclosed
US-20250295743-A1 GLYCOTARGETING THERAPEUTICS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2025-09-25 US disclosed
CN-119350116-A Method for synthesizing itaconic acid compound 南京工业大学 2025-01-24 CN disclosed
CN-115850076-B Method for introducing difluoromethylene into aromatic ring of allyl ester compound 南京工业大学 2024-11-22 CN disclosed
CN-118576700-A Sugar-targeted therapeutic agents 洛桑聚合联合学院 2024-09-03 CN disclosed
CN-118436774-A Sugar-targeted therapeutic agents 洛桑聚合联合学院 2024-08-06 CN disclosed
EP-4385520-A2 GLYCOTARGETING THERAPEUTICS Ecole Polytechnique Fédérale de Lausanne (CH) 2024-06-19 EP disclosed
US-20160243248-A1 GLYCOTARGETING THERAPEUTICS ECOLE POLYTECHNIQUE FED DE LAUSANNE (EPFL) (CH) 2016-08-25 US disclosed
US-20160015821-A1 GLYCOTARGETING THERAPEUTICS OXFORD FINANCE LLC, AS COLLATERAL AGENT 2016-01-21 US disclosed
WO-2015140648-A2 GLYCOTARGETING THERAPEUTICS ECOLE POLYTECNIQUE FEDERALE DE LAUSANNE (EPFL) EPFL-TTO (CH) 2015-09-24 WO disclosed
US-8637468-B2 Synthetic cholesterylamine-linker derivatives for agent delivery into cells THE UNIVERSITY OF KANSAS (US) 2014-01-28 US disclosed
WO-2013109907-A1 DRUG AND IMAGING AGENT DELIVERY COMPOSITIONS AND METHODS UNIVERSITY OF KANSAS (US) 2013-07-25 WO disclosed
US-20120208771-A1 SYNTHETIC CHOLESTERYLAMINE-LINKER DERIVATIVES FOR AGENT DELIVERY INTO CELLS THE PENN STATE RESEARCH FOUNDATION (US) 2012-08-16 US disclosed
WO-2011019942-A2 SYNTHETIC CHOLESTERYLAMINE-LINKER DERIVATIVES FOR AGENT DELIVERY INTO CELLS UNIVERSITY OF KANSAS (US) 2011-02-17 WO disclosed
US-20090294362-A1 STATIONARY PHASE FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2009-12-03 US disclosed
EP-0237132-A2 Process for the preparation of water-soluble saccharide polymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295743-A1 GLYCOTARGETING THERAPEUTICS B3GAT3, UGGT1, MRGPRX1 LMNA 4804/4885L3MBTL1 2270/4885ALDH1A1 2577/4885
US-20160243248-A1 GLYCOTARGETING THERAPEUTICS B3GAT3, UGGT1, MRGPRX1 LMNA 4804/4885L3MBTL1 2270/4885ALDH1A1 2577/4885
US-20120208771-A1 SYNTHETIC CHOLESTERYLAMINE-LINKER DERIVATIVES FOR AGENT DELIVERY INTO CELLS NPC1L1, CETP, CYP46A1 LMNA 339/4885L3MBTL1 1753/4885ALDH1A1 4461/4885
US-20260034226-A1 GLYCOTARGETING THERAPEUTICS LGALS1, ST6GAL1, LGALS2 LMNA 4291/4885L3MBTL1 1057/4885ALDH1A1 460/4885
US-20260007723-A1 GLYCOTARGETING THERAPEUTICS HLA-DRB1, CD74, MICA LMNA 4463/4885L3MBTL1 571/4885ALDH1A1 1398/4885
US-11654188-B2 Glycotargeting therapeutics B3GAT3, UGGT1, MRGPRX1 LMNA 4804/4885L3MBTL1 2270/4885ALDH1A1 2577/4885
US-20260115300-A1 GLYCOTARGETING THERAPEUTICS CD74, HLA-DRB1, CD69 LMNA 4625/4885L3MBTL1 2352/4885ALDH1A1 555/4885
US-20160015821-A1 GLYCOTARGETING THERAPEUTICS B3GAT3, UGGT1, MRGPRX1 LMNA 4804/4885L3MBTL1 2270/4885ALDH1A1 2577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.