Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10598338 | 0.70 | CYP1A2 (0.37) | KMT2AALDH1A1HPGDSMN1; SMN2BRD4 | |
| SCHEMBL16118411 | 0.63 | GPR3 (0.40) | KMT2AALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL7217441 | 0.63 | MAOA (0.44) | KMT2AALDH1A1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL31001160 | 0.62 | ALDH1A1 (0.46) | KMT2AALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL7144568 | 0.60 | KMT2A (0.33) | KMT2AALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL5520110 | 0.60 | NPC1 (0.58) | KMT2AALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL5901584 | 0.59 | SCD5 (0.41) | KMT2AALDH1A1HPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL5276597 | 0.59 | GPR3 (0.40) | KMT2AALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL1013979 | 0.59 | ALDH1A1 (0.44) | KMT2AALDH1A1HPGDSMN1; SMN2BRD4 | |
| SCHEMBL1423001 | 0.59 | GPR3 (0.46) | KMT2AALDH1A1HPGDSMN1; SMN2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122256-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |
| US-4052433-A | INTERMEDIATES FOR BENZOFURANS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |
| US-3994879-A | CONDENSING AZOMETHINES, OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |